Wednesday, October 28, 2015
Tuesday, October 20, 2015
11.2 Notes
Chapter 11
11.2- Reception
·
Ligand is highly specific
·
There will be a shape change in a receptor
·
Most signal proteins are plasma membrane
proteins
·
3 Receptor in plasm a membrane
o
G-Protein- coupled
o
Receptor tyrosine kinases
o
Ion channel receptors
·
G protein- coupled receptors (GPCR)
o
Largest family
o
Works with help of a G protein
o
G protein acts as an on/off switch- if GDP is
bound to the G protein, the G protein is inactive
·
Receptor tyrosine kinases (RTKs)
o
Attach phosphates to tyrosine
o
Can trigger multiple signal transduction pathways
at once
o
Abnormal functioning is associated with cancers
·
Ligand- gated ion channel
o
Acts as a gate when receptor changes shape
o
When a signal molecules binds as a ligand to the
receptor, the gate allows specific ions, such as NA+ or CA+,
through a channel in the receptor
·
Intracellular Receptor
o
Found in the cytosol or nucleus of target cells
o
Small or hydrophobic chemical messengers
§
Activate receptors
·
EX: Steroid/ Thyroid hormone
o
An activated hormone receptor complex can act as
a transcription factor, turning on specific genes
Wednesday, October 14, 2015
Read Something, Say Something
I have shared two articles with you in class. The first was Tiny Cavers, about the discovery of a new early human species. The second was Overthinking Worriers, about how overthinking worriers may be creative geniuses. Please read one of these articles and write a comment below, tell us what article you read and tell us about what you thought was most interesting in that article.
Tuesday, October 13, 2015
Monday, October 12, 2015
Thursday, October 8, 2015
Drawing Flies - Biology Comics
If you need to study, but need a little comic relief as well, check out the Drawing Flies Blog. Go learn something!
Tuesday, October 6, 2015
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